Terverifikasi Administratif dan Faktual oleh Dewan Pers
Pesaing Quartararo, Johann Zarco adalah salah satu yang gagal finis.
Kemudian Alex Rins, Valentino Rossi, Jack Miller, dan Pol Espargaro adalah pembalap lainnya yang gagal menyelesaikan balapan kali ini.
Berikut adalah hasil lengkap MotoGP Portugal 2021:
| Pos. | Points | Num. | Rider | Nation | Team | Bike | Km/h | Time/Gap |
|---|---|---|---|---|---|---|---|---|
| 1 | 25 | 20 | Fabio QUARTARARO | FRA | Monster Energy Yamaha MotoGP | Yamaha | 164.8 | 41'46.412 |
| 2 | 20 | 63 | Francesco BAGNAIA | ITA | Ducati Lenovo Team | Ducati | 164.5 | +4.809 |
| 3 | 16 | 36 | Joan MIR | SPA | Team SUZUKI ECSTAR | Suzuki | 164.5 | +4.948 |
| 4 | 13 | 21 | Franco MORBIDELLI | ITA | Petronas Yamaha SRT | Yamaha | 164.5 | +5.127 |
| 5 | 11 | 33 | Brad BINDER | RSA | Red Bull KTM Factory Racing | KTM | 164.4 | +6.668 |
| 6 | 10 | 41 | Aleix ESPARGARO | SPA | Aprilia Racing Team Gresini | Aprilia | 164.3 | +8.885 |
| 7 | 9 | 93 | Marc MARQUEZ | SPA | Repsol Honda Team | Honda | 164.0 | +13.208 |
| 8 | 8 | 73 | Alex MARQUEZ | SPA | LCR Honda CASTROL | Honda | 163.7 | +17.992 |
| 9 | 7 | 23 | Enea BASTIANINI | ITA | Avintia Esponsorama | Ducati | 163.4 | +22.369 |
| 10 | 6 | 30 | Takaaki NAKAGAMI | JPN | LCR Honda IDEMITSU | Honda | 163.3 | +23.676 |
| 11 | 5 | 12 | Maverick VIÑALES | SPA | Monster Energy Yamaha MotoGP | Yamaha | 163.3 | +23.761 |
| 12 | 4 | 10 | Luca MARINI | ITA | SKY VR46 Avintia | Ducati | 162.9 | +29.660 |
| 13 | 3 | 9 | Danilo PETRUCCI | ITA | Tech 3 KTM Factory Racing | KTM | 162.9 | +29.836 |
| 14 | 2 | 32 | Lorenzo SAVADORI | ITA | Aprilia Racing Team Gresini | Aprilia | 162.3 | +38.941 |
| 15 | 1 | 27 | Iker LECUONA | SPA | Tech 3 KTM Factory Racing | KTM | 161.6 | +50.642 |
| 16 | 88 | Miguel OLIVEIRA | POR | Red Bull KTM Factory Racing | KTM | 157.2 | 1 Lap | |
| Not Classified | ||||||||
| 5 | Johann ZARCO | FRA | Pramac Racing | Ducati | 164.5 | 6 Laps | ||
| 42 | Alex RINS | SPA | Team SUZUKI ECSTAR | Suzuki | 164.8 | 7 Laps | ||
| 46 | Valentino ROSSI | ITA | Petronas Yamaha SRT | Yamaha | 163.1 | 11 Laps | ||
| 43 | Jack MILLER | AUS | Ducati Lenovo Team | Ducati | 162.9 | 20 Laps | ||
| 44 | Pol ESPARGARO | SPA | Repsol Honda Team | Honda | 150.7 | 21 Laps | ||